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Symbol Name ID |
Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1 MGI:99137 |
| Darker colors indicate more annotations |
| Human Phenotypes | Anorexia |
Dysphagia |
Oculomotor apraxia |
Cerebellar atrophy |
Dysdiadochokinesis |
Dysmetria |
Gait ataxia |
Limb ataxia |
Dysarthria |
Areflexia |
Unsteady gait |
Sensorimotor neuropathy |
Impaired distal proprioception |
Impaired distal vibration sensation |
Positive Romberg sign |
| Disease(s) Associated with XRCC1 | |||||||||||||||
| autosomal recessive spinocerebellar ataxia 26 | |||||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | seizures |
increased neuron apoptosis |
abnormal neuron differentiation |
abnormal brain interneuron morphology |
decreased brain size |
abnormal brain white matter morphology |
small cerebellum |
loss of GABAergic neurons |
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| Availability | Mouse Genotype | ||||||||
| Xrcc1tm1Pmc/Xrcc1tm1Pmc Tg(Nes-cre)1Kln/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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